Vascular and sympathoadrenal responses to bradykinin and a bradykinin analogue.
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منابع مشابه
Vascular and sympathoadrenal responses to bradykinin and a bradykinin analogue.
These experiments were designed to assess the interaction of bradykinin and its antagonist (Arg-Pro-Hyp-Gly-Phe-Ser-DPhe-Phe-Arg-trifluoroacetic acid) with the sympathoadrenal system. Three groups of male Wistar rats received 5-minute intra-arterial infusions of either dextrose (Group 1, n = 6), bradykinin, 250 micrograms/min (Group 2, n = 5), or bradykinin, 25 micrograms/min (Group 3, n = 4). ...
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Background and purpose: Chronic kidney disease is among the common diseases in the world. Studies show that women are more protected against renal diseases compared to men. On the other hand, vasodilatory axises of renin angiotensin system (angiotensin 1-7 (Ang 1-7)- Mas receptor (MasR)), kallikrein-kinin, and nitric oxide (NO) play key roles in kidney function and circulation in females. There...
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Angiotensin-converting enzyme (ACE) is known to catalyze the conversion of angiotensin I to angiotensin II and degrades bradykinin and other vasoactive peptides. The fact that ACE participates in the degradation of bradykinin has led to the postulate that the beneficial renal and cardiovascular actions of ACE inhibitors can be attributed to augmenting and prolonging the effects of bradykinin. T...
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DOISIN are vasoactive polypeptides recently synthesized in pure form.1-3 Bradykinin and kallidin exist in man, whereas eledoisin has been found only in the posterior salivary glands of Eledone. Although the three poly-peptides have potent vasodilating and hypo-tensive properties, only bradykinin and kallid-in are closely related structurally (fig. 1). The nonapeptide structure of bradykinin was...
متن کاملPreparation of a Photoactivable Ligand for Bradykinin Receptors
ABSTRACT Most of physiological effects of bradykinin is due to its effect on bradykinin B2 receptors. There is no reports of preparation of a photoactivatable analogue of bradykinin reactive with sloubilized bradykinin B2 recpetors. Photoactivatable radioactive ligands are powerful tools in purification of receptors. In this study we report preparation of a photoactivatable iodinatable analo...
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ژورنال
عنوان ژورنال: Hypertension
سال: 1988
ISSN: 0194-911X,1524-4563
DOI: 10.1161/01.hyp.11.6.754